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Unraveling the mechanisms underlying AED guerillas has been the woolly of powerful efforts, in orderliness to develop new rationally designed therapies for as despite everything refractory epilepsies. Descry Tripolar concentric bandeau electrode (TCRE) Temporal lobe epilepsy (TLE) cell death cubicle pattern regulation, 83В­84 excitotoxicity, 80 external pathway, 81В­82 natural pathway, 82 mitochondrial outer membrane (MOMP), 82 p53-upregulated mediator of apoptosis (PUMA), 82В­83 ROS production, 82 epileptogenesis, 79В­80 neuronal end Cdk1 hyperexpression, 89 lithiumВ­pilocarpine model, 88В­89 p53 accumulation, 89 phosphorylated ERK, 89 signalling in patients, 90В­91 proteomics cubicle signaling, 118 chaperone, 118 dihydropyrimidinase-related protein 2 (DPYSL2), 120В­121 2D-PAGE image, 119В­120 epileptogenesis, 118 GAERS and WAG/Rij, 122 glutathione S-transferase P (GSTP1), 121 guanine nucleotide-binding protein (G proteins), 122 hippocampal sclerosis (HS), 117В­118 MALDI-TOF, 117 mesial non-ecclesiastical lobe epilepsy (MTLE), 117 pilocarpine-induced epilepsy, 121, 122 transcriptional signaling, 118В­119 survival/cell devastation, signal pathways extracellular signal regulated kinases (ERK), 85В­86 JAK/STAT and PI3K/AKT pathways, 86В­88 JNK pathway, 86 proinflammatory mediators, 84 stress-activated protein kinases (SAPK), 86 Tergau, F. 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